Best Natural Pain Relief Creams [Ranked + Reviewed]

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Best Natural Pain Relief Cream

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If you feel like you’re in constant pain, whether you have a chronic condition or an acute one, you could benefit from using a natural pain relief cream.

These natural salves work using either cold or hot therapy, and often use counterirritants to block out the sensation of pain.

They can be very effective for managing pain, so it’s worth having a natural pain relief cream within reach at all times.

Here are our top picks…

👑 Our Pick for Best Overall

[amazon box=”B00DI7U88G” title=”Penetrex Relief & Recovery Cream” description=”If you like the sound of a pain relief cream that does the job well and leaves behind no trace, then you’ll love Penetrex’s cream. It’s formulated using only natural ingredients, and is praised by many for how well it relieves pain from a variety of conditions, both acute and chronic.”]

Our Other Top Picks for Natural Pain Relief Cream

Best Natural Pain Relief Cream Reviews

Penetrex Relief & Recovery Cream (👑 Best of the Best)

Number one in our list of the best natural pain relief creams has to be Penetrex’s Relief & Recovery Cream.

If you’re looking for effective pain relief, and fast, then there are few better options than this cream from Penetrex. It’s so good, in fact, that it was voted the #1 Best Overall Muscle Rub for 2019 by huge publication Business Insider. If that isn’t convincing enough, then perhaps the thousands of past customers that sing his product’s praises should help. 

Penetrex’s cream comes in a 4oz tub, and the star ingredients are arnica, vitamin B6 and MSM. If you haven’t heard of arnica before, you’re in for a treat. Arnica is a herb that is often found in pain relief skins because of its ability to soothe the skin. As well as this herb, there are several other natural ingredients that make this a pain-relieving powerhouse such as vitamin B6 and MSM. MSM is a naturally-occuring substance that pops up in primitive plants, and vitamin B6 is found in many foods and hlps with cognitive development and healthy immune function. Together, the three ingredients combine to reduce inflammation and soothe pain from a variety of sources. People use this cream to address pain in the neck (the literal kind), the knees, the hands, the feet, and more.

What’s more, this natural pain relief cream can be used alongside complementary therapies. So if you use arthritis gloves or carpal tunnel braces for example, you can get extra comfort from doubling up and giving your hands and fingers the love they deserve. Another property of the cream that many enjoy is its non-greasy and non-staining nature. This means that you don’t have to worry about walking around all day with greasy hands or cream residue. The cream is also free from parabens and has never been tested on animals. You also don’t have to worry about a strong odor, since Penetrex only has a light scent which soon vanishes. 

Past customers have heaped praise on this natural pain relief cream, and many of them claim to always keep a jar of Penetrex nearby for when things get painful. In particular, customers seem to like that it absorbs completely into the skin, and that it can help with everything from chronic illnesses such as arthritis and carpal tunnel to knee problems and more.

Perhaps best of all is the 100% money-back guarantee offered by Penetrex. This generous guarantee ensures that your investment is safe and secure, since if you don’t get the results you’re looking for, you have the option of getting all of your money back. So you can essentially try before you buy, and see if the pain relief cream works as well for you as it seems to for so many others.


  •  Includes vitamin B6. MSM, and Arnica
  •  4oz tub
  •  Cruelty-free
  •  Non-greasy and non-staining
  •  Vanishing scent
  •  Paraben-free
  •  100% money-back guarantee

Rub on Relief Natural Cream (🥈 Runner Up)

If you need instant relief from pain in the joints, or a chronic condition like arthritis, then Rub on Relief could be your best option.

The small 3oz toothpaste-like tube is the perfect topical cream for dealing with soremuscles and joints. As a results, it’s an excellent option for the athlete or the recreational sports enthusiasts who suffers from pain following exercise sometimes. The cream is formulated using only the best natural ingredients, and there are many – 13 to be precise. The ingredients are all clinically tested and include MSM, CMO, lemon and lime oil, white willow extract, magnesium sulfate, arnica, curcumin, peppermint leaf oil, and more.

This rub on cream is designed for pain relief all over the body, from the hands and fingers, to the knees and elbows, and everything in between. The cream penetrates the skin to provide soothing relief to sore muscles and joints when they are screaming in agony. The product is formulated by an expert medical advisory board, using an all-star lineup of natural ingredients, each of which lends its healing properties to the mix. As well as being made up purely of natural ingredients, Rub on Relief is free from foul odors, greasiness, burn, and anything toxic. That means when you apply it to your skin, you won’t recoil at the burning sensation or lament the greasy layer of film it leaves behind since there won’t be one.

Diving into the customer reviews left on the product’s Amazon page, it’s clear to see that people who have tried Rub on Relief have enjoyed it immensely. One user talks of how the product is helping them recover from severe osteoarthtiic of the ankle, while another claims that it is helping to keep the searing pain of a pinched sciatic nerve at bay. Each of the stories brought up in the reviews speak to the effectiveness of the cream, so it’s worth taking a look for yourself, to see if someone with a similar type of pain as you has experienced relief from using it.

Then there’s the 100% money-back guarantee, which secures your investment, and makes sure that you aren’t left feeling like you wasted your money. Either you get a pain relief cream that works as well as many past customers claim it does, or you get your money back.


  •  Includes 13 natural ingredients 
  •  3oz squeeze tube
  •  Non-greasy
  •  Free from chemicals and preservatives
  •  100% money-back guarantee
[amazon box=”B009SQ7U28″ title=”Rub on Relief Natural Cream” description=”Rub on Relief is an excellent option if you want something that’s quick and easy to apply. It’s hands-down the best option for athletes and those who tend to experience joint and muscle pain as a result of exercise.”]

Tiger Balm Red Extra Strength (⭐ Best on a Budget)

Our budget pick for the best natural pain relief cream is Tiger Balm, which has an outstanding reputation for being an incredible pain relief cream that costs a mere fraction of many alternatives.

If you’re looking for a miracle pain relief cream that will cost you little more than a coffee, then you needn’t look further. Tiger Balm Red Extra Strength is widely regarded, which is backed up by its Amazon’s Choice label and its thousands of glowing reviews. It’s one of those products that you feel shouldn’t work due to its low price, but somehow does, and exceeds all expectations.

The cream comes in a 0.16lb tub, and is made from camphor, menthol, cajuput oil, cassia oil, clove oil, dementholized mint oil, and paraffin petrolatum. These ingredients combine to make an effective pain-relieving elixir which should melt away your aches and pains in no time at all. Camphor is a topical analgesic which provides relief for sore muscles and joints, menthol provides that soothing cooling sensation and the variety of oils work together to seep into the skin and provide a deeper level of comfort and relief from pain.

The product works for everything from overexertion to backaches, and even chronic conditions such as arthritis. It has also been shown to be effective for treating stiffness and aches in the muscles and joints. It’s perfect for use before or after a workout, and many people swear by it. Many previous customers claim that this pain relief cream is a cure-all for whatever ails you. They say that it works as well for headaches and stomach aches as it does for more severe health conditions like arthritis and long term knee pain.


  •  0.16lbs jar
  •  Includes a variety of soothing ingredients
[amazon box=”B002RLR8WS” title=”Tiger Balm Red Extra Strength” description=”Tiger Balm Red Extra Strength is the pain relief cream you can rely on regardless of your budget. It is both incredibly affordable and effective, which makes it the perfect choice for those who don’t want to spend a fortune on expensive creams.”]

Ultimate Guide

In order to get the best natural pain relief cream for you, there are several factors you’ll need to bear in mind.

The ingredients of any pain relief cream are important, so we’ve dedicated a whole section to them.

Another factor which should have a significant influence on your purchase decision is the quality of the cream, which can be determined in several ways, which we’ll also cover.

But first, before we get into the specifics of the individual products, we’d like to take a step back and look at what exactly pain relief creams are so you can get a clear idea of whether they can work for you.

What is a natural pain relief cream?

A natural pain relief cream is a topical ointment which is intended to relieve pain in the muscles and the joints. Using a mixture of natural herbs and oils, these creams can provide a cooling or hot sensation and temporary block the feeling of pain. They can be used by anyone for pretty much any kind of external pain, be it wrist and hand pain, knee pain, or leg pain.

One of the most common uses for natural pain relief cream, though, is for helping those with chronic health conditions like arthritis manage their pain. Many topical relief creams penetrate the skin and work into the joints which makes them great for getting to the root of the issue, and in the case of those with arthritis, easing the pain that can seem constant.

The mechanisms that these creams rely on tend to be anti inflammatory properties and numbing agents, as well as hot and cold therapy. While there is no guarantee that they will work for everyone, many people swear by pain relief creams so there’s a good chance that you’ll be able to find one that works for you.

Best Ingredients

The following ingredients are considered to be some of the most effective when it comes to relieving pain, so if you see them on the label of a pain relief cream, that’s a great sign.


MSM, which is short for Methylsulfonylmethane is a naturall-occuring sulfur from plants which can intercept the message of pain before it reaches the brain. 

It has also been shown to reduce inflammation and soothe swelling.


CMO is a fatty acids which helps prevent the friction of dry joints rubbing up against each other. It works into the tissues of the muscles as well as the joints to soothe inflammation, and can reduce pain.

White Willow Extract

White willow extract is often referred to as ‘Mother Nature’s Aspirin’, which tells you all you need to know about its effectiveness in reducing pain.


Arnica is a flower commonly used in natural pain relief creams due to its ability to decrease swelling and reduce pain.


Camphor is a natural gum which provides a warming sensation that can give you the feeling of havin heat therapy, which should feel great and should soothe any pain that you’re experiencing.


The quality of the natural pain relief cream can be hard to determine, but there are a few key indicators that you’re onto a winner.


The first thing you should look out for is the mix of ingredients used in the pain relief cream. This will give you a clear idea of whether or not it’s worth giving a try.

If it doesn’t seem like there’s a healthy dose of proven pain-relieving ingredients, and that is reinforced by poor user reviews, then you should probably steer clear.


While you should of course take the Amazon star rating of the product with a pinch of salt, there is definitely something to be gleaned from it.

Many customers try their best to provide honest feedback about a product they’ve bought, and when it comes to pain relief, the product is either effective or it isn’t, and this will be reflected in the rating.

With the rating, you should also pay attention to how many people have left one. If five people have left five-star reviews, you shouldn’t put too much stock into it. But if tens of thousands of people almost unanimously agree that this product is worth five stars, then you know you’re onto something good.


It’s easy to get caught up in reviews and put too much stock into them, but they are there for a reason, and it’s worth taking a look. This is especially true of natural products, since there isn’t likely going to be much else to go on.

Look for the reviews that seem well-thought out, as these are most likely coming from someone who wants to give a detailed and honest opinion in order to inform others of whether they should buy or not.

Frequently Asked Questions About Pain Relief Cream

What is the best cream for pain relief?

We believe that the best cream for pain relief is Penetrex’s Relief & Recovery Cream.

This cream won an award from Business Insider and has thousands of past customers who swear by it.

It’s also non-greasy and non-staining which means it vanishes without leaving a trace soon after application, as does the scent.

Are topical creams good for joint pain?

Yes, topical creams can be very effective for reducing and managing joint pain.

Many people who suffer with arthritis swear by pain relief creams, claiming that they can do a world of good for you when nothing else seems to help.

They contain a variety of ingredients which can penetrate the skin and block the sensation of pain while providing a soothing cooling or hot feeling.

How can I get natural pain relief?

There are many things you can try to get pain relief without resorting to medicine.

For instance, you can try acupuncture or some form of heat or cold therapy, as these are both shown to be effective for reducing pain in the muscles.

Alternatively, you can give natural pain relief creams a go, since they can provide fast-acting pain relief so you can get back to doing what you love in no time.

A Final Word From Wellness Nova

Pain relief cream can be a real lifesaver, and it’s something that you should always have at home for when your muscles or joints start to give you grief. Choosing between all the natural pain relief creams can be tough, but once you’ve figured out your priorities you should be able to make an informed decision.

Article by:

Wellness Nova Team

Our detailed review has been contributed to by multiple members of the Wellness Nova Review Team to ensure the best research and highest standard of quality. Have a good or a bad experience with one of the products? Please let us know, we love the feedback!

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